Asheville District
- AS-Line (Salisbury – TN Border)
- ECBU (Selma East)
- O-Line/L-Line (Winston-Salem – Charlotte)
Charleston District
- SB-Line (Rock Hill – Catawba, SC)
- SC-Line (Columbia – Charleston)
Charlotte District
- Mainline (Linwood – Greenville)
- N-Line (Salisbury – Albemarle)
- M-Line (High Point – Asheboro)
Columbia District
- R-Line (Charlotte – Augusta)
- W-Line (Landrum – Columbia)
Danville District
- Mainline (VA Border – Linwood)
- NC-Line (Greensboro – Selma)
- K-Line (Greensboro – Winston-Salem)
- CF-Line (Greensboro – Gulf)
Greenville District
- Mainline (Greenville – GA Border)